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Towards an integrated modeling of the plasma-solid interface

Michael Bonitz, Alexey Filinov, Jan-Willem Abraham, Karsten Balzer, Hanno Kählert, Eckhard Pehlke, Franz X. Bronold, Matthias Pamperin, Markus Becker, Dettlef Loffhagen, Holger Fehske

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 2,   Pages 201-237 doi: 10.1007/s11705-019-1793-4

Abstract: The fourths are nonequilibrium Green functions that able to treat correlation effects in the material

Keywords： plasma physics     surface science     plasma-surface modeling     DFT     nonequilibrium Green functions    

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An autonomous system for thermal convection of viscoelastic fluids in a porous layer using a thermal nonequilibrium

Qi WEI, Xiaohui ZHANG

Frontiers in Energy 2010, Volume 4, Issue 4,   Pages 507-516 doi: 10.1007/s11708-010-0017-x

Abstract: viscoelastic fluids saturating a horizontal porous layer heated from below is analyzed using a thermal nonequilibrium

Keywords： thermal convection     porous media     viscoelastic fluid     thermal nonequilibrium model    

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Research of Refinement Methods of Dynamic Model Based on Frequency Response Functions

Zhu Dangdang,Feng Yaoqi,Xiang Shuhong

Strategic Study of CAE 2005, Volume 7, Issue 8,   Pages 89-94

Abstract: dynamic model improvement methods, and researched the refinement methods based on frequency and response functionsIn order to make the full use of the frequency and response functions obtained in the vibration test,the paper introduced three dynamic model improvement methods with frequency and response functions such

Keywords： spacecraft     dynamics     frequency and response functions     model refinement    

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Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 2144-2155 doi: 10.1007/s11705-023-2362-4

Abstract: This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities, in addition to luminescence. The activity of the silica nanoparticles is derived from their plasmonic properties, which are a result of infusing the silica nanoparticles with multiple Cu2–xS cores. This infusion process is facilitated by a recoating of the silica nanoparticles with a cationic surfactant. The key factors that enable the internal incorporation of the Cu2–xS cores and the external deposition of red-emitting carbon dots are identified. The Cu2–xS cores within the silica nanoparticles exhibit both self-boosting generation of reactive oxygen species and high photothermal conversion efficacy, which are essential for photothermal and chemodynamic activities. The silica nanoparticles’ small size (no more than 70 nm) and high colloidal stability are prerequisites for their cell internalization. The internalization of the red-emitting silica nanoparticles within cells is visualized using fluorescence microscopy techniques. The chemodynamic activity of the silica nanoparticles is associated with their dark cytotoxicity, and the mechanisms of cell death are evaluated using an apoptotic assay. The photothermal activity of the silica nanoparticles is demonstrated by significant cell death under near-infrared (1064 nm) irradiation.

Keywords： copper sulfide nanoparticles     chemodynamic therapy     photothermal therapy     carbon dots     silica nanoparticles    

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Ground-to-Air Radar Jamming Syste——Functions in Current Local Conflict and Its Development Trend

Zhang Xixiang

Strategic Study of CAE 2000, Volume 2, Issue 7,   Pages 55-65

Abstract: It has both defensive and offensive functions with its 3D jamming capabilities.

Keywords： ground-to-air jamming system     functions in current conflict     development trend    

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Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 639-645 doi: 10.1007/s11684-019-0701-0

Abstract: carotid body, adrenal glands, choroid plexus, and leukocytes among others, where it exerts distinct functions

Keywords： tumor suppressor gene     esophageal cancer-related gene-4     cardiovascular disease     hypoxia    

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Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the

Frontiers of Medicine   Pages 924-938 doi: 10.1007/s11684-023-1004-z

Abstract: Long noncoding RNAs (lncRNAs) play a crucial regulatory role in the development and progression of multiple cancers. However, the potential mechanism by which lncRNAs affect the recurrence and metastasis of ovarian cancer remains unclear. In the current study, the lncRNA LOC646029 was markedly downregulated in metastatic ovarian tumors compared with primary tumors. Gain- and loss-of-function assays demonstrated that LOC646029 inhibits the proliferation, invasiveness, and metastasis of ovarian cancer cells in vivo and in vitro. Moreover, the downregulation of LOC646029 in metastatic ovarian tumors was strongly correlated with poor prognosis. Mechanistically, LOC646029 served as a miR-627-3p sponge to promote the expression of Sprouty-related EVH1 domain-containing protein 1, which is necessary for suppressing tumor metastasis and inhibiting KRAS signaling. Collectively, our results demonstrated that LOC646029 is involved in the progression and metastasis of ovarian cancer, which may be a potential prognostic biomarker.

Keywords： ovarian cancer     lncRNA LOC646029     metastasis     microRNA 627-3p     SPRED1    

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The use of Artificial Neural Networks to estimate seismic damage and derive vulnerability functions for

Tiago Miguel FERREIRA, João ESTÊVÃO, Rui MAIO, Romeu VICENTE

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 3,   Pages 609-622 doi: 10.1007/s11709-020-0623-6

Abstract: This paper discusses the adoption of Artificial Intelligence-based techniques to estimate seismic damage, not with the goal of replacing existing approaches, but as a mean to improve the precision of empirical methods. For such, damage data collected in the aftermath of the 1998 Azores earthquake (Portugal) is used to develop a comparative analysis between damage grades obtained resorting to a classic damage formulation and an innovative approach based on Artificial Neural Networks (ANNs). The analysis is carried out on the basis of a vulnerability index computed with a hybrid seismic vulnerability assessment methodology, which is subsequently used as input to both approaches. The results obtained are then compared with real post-earthquake damage observation and critically discussed taking into account the level of adjustment achieved by each approach. Finally, a computer routine that uses the ANN as an approximation function is developed and applied to derive a new vulnerability curve expression. In general terms, the ANN developed in this study allowed to obtain much better approximations than those achieved with the original vulnerability approach, which has revealed to be quite non-conservative. Similarly, the proposed vulnerability curve expression was found to provide a more accurate damage prediction than the traditional analytical expressions.

Keywords： Artificial Neural Networks     seismic vulnerability     masonry buildings     damage estimation     vulnerability curves    

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Enhancement of the polynomial functions response surface model for real-time analyzing ozone sensitivity

Jiangbo Jin, Yun Zhu, Jicheng Jang, Shuxiao Wang, Jia Xing, Pen-Chi Chiang, Shaojia Fan, Shicheng Long

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 2, doi: 10.1007/s11783-020-1323-0

Abstract: An Enhanced polynomial functions Response Surface Model (Epf-RSM) with the capability to analyze O3-NOx-VOCSeveral comparisons between Epf-RSM and pf-ERSM (polynomial functions based ERSM) were performed using

Keywords： Response surface model     Hill-climbing algorithm     Ozone pollution     Precursor emissions     Control strategy    

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Physiological functions and clinical implications of the N-end rule pathway

Yujiao Liu,Chao Liu,Wen Dong,Wei Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 258-270 doi: 10.1007/s11684-016-0458-7

Abstract: The molecular basis of the N-end rule pathway has been elucidated and its physiological functions haveThis review summarized the physiological functions of the N-end rule pathway, introduced the related

Keywords： N-end rule pathway     Ate1     cardiovascular development     neurogenesis     spermatogenesis     neurodegenerative disorders     Johanson–Blizzard syndrome    

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Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast

Xuran Chu, Chengshui Chen, Chaolei Chen, Jin-San Zhang, Saverio Bellusci, Xiaokun Li

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 262-272 doi: 10.1007/s11684-019-0717-5

Abstract: Regeneration carries the idea of regrowing partially or completely a missing organ. Repair, on the other hand, allows restoring the function of an existing but failing organ. The recognition that human lungs can both repair and regenerate is quite novel, the concept has not been widely used to treat patients. We present evidence that the human adult lung does repair and regenerate and introduce different ways to harness this power. Various types of lung stem cells are capable of proliferating and differentiating upon injury driving the repair/regeneration process. Injury models, primarily in mice, combined with lineage tracing studies, have allowed the identification of these important cells. Some of these cells, such as basal cells, broncho-alveolar stem cells, and alveolar type 2 cells, rely on fibroblast growth factor (FGF) signaling for their survival, proliferation and/or differentiation. While pre-clinical studies have shown the therapeutic benefits of FGFs, a recent clinical trial for acute respiratory distress syndrome (ARDS) using intravenous injection of FGF7 did not report the expected beneficial effects. We discuss the potential reasons for these negative results and propose the rationale for new approaches for future clinical trials, such as delivery of FGFs to the damaged lungs through efficient inhalation systems, which may be more promising than systemic exposure to FGFs. While this change in the administration route presents a challenge, the therapeutic promises displayed by FGFs are worth the effort.

Keywords： FGF     human lung     repair     regeneration     stem cells    

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Identifying subassemblies and understanding their functions during a design review in immersive and non-immersive

Fanika LUKAČEVIĆ, Stanko ŠKEC, Peter TÖRLIND, Mario ŠTORGAL

Frontiers of Engineering Management 2021, Volume 8, Issue 3,   Pages 412-428 doi: 10.1007/s42524-020-0099-z

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Innovation Ecosystem for Green Smart City Building in China

Jin Chen

Frontiers of Engineering Management 2015, Volume 2, Issue 4,   Pages 325-330 doi: 10.15302/J-FEM-2015058

Abstract: Green Smart City (GSC), is one of the new types of cities which integrates eco-concepts and information

Keywords： green smart city     resource     innovation ecosystem building    

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Potential advantages in combining smart and green infrastructure over silo approaches for future cities

Yamuna KALUARACHCHI

Frontiers of Engineering Management 2021, Volume 8, Issue 1,   Pages 98-108 doi: 10.1007/s42524-020-0136-y

Abstract: Cities are incorporating smart and green infrastructure components in their urban design policies, adaptingResearch has illustrated that smart green infrastructure (SGI) provides not only climate change resilienceThis paper explores the potential to transition from grey, green, or smart silos to work with nature-basedThe concepts of grey, green, and smart infrastructure are presented, and the needs, benefits, and applicationsMoreover, the advantages of using integrated smart, green nature-based solutions are discussed.

Keywords： grey infrastructure     green infrastructure     smart infrastructure     smart and green combined infrastructure    

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A Fault Location Approach for the Testable Realization of Logic Functions

Pan Zhongliang

Strategic Study of CAE 2002, Volume 4, Issue 1,   Pages 69-74

Abstract:

An approach of design for testability(DFT) for logic functions is presented in the paper, which employsAND gates and XOR gates tree to realize the generalized Reed-Muller expression of arbitrary logic functions

Keywords： logic functions     Reed-Muller expressions     design for testability     single stuck at fault     faults location    

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Title Author Date Type Operation

Towards an integrated modeling of the plasma-solid interface

Michael Bonitz, Alexey Filinov, Jan-Willem Abraham, Karsten Balzer, Hanno Kählert, Eckhard Pehlke, Franz X. Bronold, Matthias Pamperin, Markus Becker, Dettlef Loffhagen, Holger Fehske

Journal Article

An autonomous system for thermal convection of viscoelastic fluids in a porous layer using a thermal nonequilibrium

Qi WEI, Xiaohui ZHANG

Journal Article

Research of Refinement Methods of Dynamic Model Based on Frequency Response Functions

Zhu Dangdang,Feng Yaoqi,Xiang Shuhong

Journal Article

Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

Journal Article

Ground-to-Air Radar Jamming Syste——Functions in Current Local Conflict and Its Development Trend

Zhang Xixiang

Journal Article

Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Journal Article

Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the

Journal Article

The use of Artificial Neural Networks to estimate seismic damage and derive vulnerability functions for

Tiago Miguel FERREIRA, João ESTÊVÃO, Rui MAIO, Romeu VICENTE

Journal Article

Enhancement of the polynomial functions response surface model for real-time analyzing ozone sensitivity

Jiangbo Jin, Yun Zhu, Jicheng Jang, Shuxiao Wang, Jia Xing, Pen-Chi Chiang, Shaojia Fan, Shicheng Long

Journal Article

Physiological functions and clinical implications of the N-end rule pathway

Yujiao Liu,Chao Liu,Wen Dong,Wei Li

Journal Article

Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast

Xuran Chu, Chengshui Chen, Chaolei Chen, Jin-San Zhang, Saverio Bellusci, Xiaokun Li

Journal Article

Identifying subassemblies and understanding their functions during a design review in immersive and non-immersive

Fanika LUKAČEVIĆ, Stanko ŠKEC, Peter TÖRLIND, Mario ŠTORGAL

Journal Article

Innovation Ecosystem for Green Smart City Building in China

Jin Chen

Journal Article

Potential advantages in combining smart and green infrastructure over silo approaches for future cities

Yamuna KALUARACHCHI

Journal Article

A Fault Location Approach for the Testable Realization of Logic Functions

Pan Zhongliang

Journal Article